Allergic Diseases

Question: What is the major disadvantage of the adaptive immune system?


The disadvantage of the adaptive immunes response is that the required expansion process takes time after the first encounter with antigen, in some cases more than 2 weeks. Many infectious agents can cause death or severe disability in less time than it takes the adaptive immune system to mobilize a specific response. This disadvantage leaves a gap in the host defense system.

Reference:  Abbas AK, Lichtman AH: Cellular and Molecular Immunology, 5th ed. Philadelphia, W.B. Saunders, 2003.

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