Allergic Diseases

Archive for the 'Uncategorized' Category

Question: Does grass allergen tablet immunotherapy (Grazax) relieves individual seasonal eye and nasal symptoms, including nasal blockage?

Tuesday, October 23rd, 2007

Answer: Grazax has effects on multiple allergic symptoms, including nasal blockage, and is an effective treatment of rhinoconjunctivitis, thereby reducing the need for topical anti-allergic drugs. Symptoms of allergic rhinitis have a considerable impact on the quality of life of the sufferer. Sneezing, runny nose, blocked nose and headache are some of the most common […]

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Question: Is short course corticosteroids (oral, intramuscular, or intravenous) beneficial for preventing relapse after an acute exacerbation of asthma?

Monday, October 22nd, 2007

Answer: A short course of corticosteroids following assessment for an asthma exacerbation significantly reduces the number of relapses to additional care, hospitalizations and use of short-acting beta(2)-agonist without an apparent increase in side effects. Intramuscular and oral corticosteroids are both effective. Acute asthma is responsible for many emergency department (ED) visits annually. Between 12 to […]

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Question: Is swimming beneficial in patient with mild persistent asthma?

Sunday, October 21st, 2007

Answer: Engagement of patients with mild persistent asthma in recreational swimming in nonchlorinated pools, combined with regular medical treatment and education, leads to better improvement of their parameters of lung function and also to more significant decrease of their airway hyperresponsiveness compared to patients treated with traditional medicine. Study was done to analyzed the effect […]

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Question: Is acupuncture effective and safe in patient with persistent allergic rhinitis?

Sunday, October 21st, 2007

Answer: Findings suggest that acupuncture is effective in the symptomatic treatment of persistent allergic rhinitis.Expert investigated the effectiveness and safety of acupuncture in persistent allergic rhinitis (PAR). They did a randomised, single-blind, sham-controlled trial conducted from May 2004 to February 2005. 80 patients with PAR (age, 16-70 years) were randomly assigned to receive real or […]

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Question: A 20 year-old patient presents with hypotension, wheezing, and urticaria 30 minutes after a bee sting. What is the appropriate treatment?

Friday, October 12th, 2007

Answer: This patient’s presentation is that of systemic anaphylaxis. Anaphylaxis is an immediate hypersensitivity reaction caused by mast cell/basophil release of multiple potent mediators, including histamine, prostaglandins, and leukotrienes, into tissues and the circulation. Prompt treatment is critical, and therapy should be directed toward maintaining cardiovascular and pulmonary function. Initial treatment should be administration of […]

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Which class of medication should be used with particular caution in patients prone to develop anaphylaxis?

Thursday, September 20th, 2007

Beta blockers should be avoided whenever possible, because they may accentuate the severity of anaphylaxis and prolong its cardiovascular and pulmonary manifestations. They may also markedly decrease the effectiveness of epinephrine in reversing the life-threatening manifestation of anaphylaxis

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What is the Chinese restaurant syndrome?

Thursday, September 20th, 2007

It is a reaction to glutamate ingested as MSG (monosodium glutamate), a flavoring agent commonly used in Chinese cooking. It occurs within 15-30 minutes of ingestion and consists of a sensation of warmth and tightness on the face and anterior chest. It isĀ  occasionally confused with angina pectoris, but is benign and requires no therapy […]

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What is the “innocent bystander” mechanism of drug-induced hemolysis?

Wednesday, September 5th, 2007

Some drugs (such as sulfonamides, phenothiazines, quinidine, and quinine) can cause an immune hemolytic anemia even though they do not bind to RBCs. These drugs, bound to plasma proteins, stimulate the formation of complement-fixing antibodies that activate the classical complement pathway. Generated C3b binds to the RBC, which leads to intravascular hemolysis of these”innocent bystanders“.

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What is the predictive value of skin testing for Penicillin allergy?

Wednesday, September 5th, 2007

Negative skin testing in patients with a positive prior history indicates that clinically significant amounts of IgE antibodies against penicillin are not present and the risk of anaphylaxis is extremely low. When an allergic reaction occurs in these patients it is usually not life-threatening. A positive reaction with skin testing indicates that the patient is […]

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What are the indications for skin testing for penicillin allergy?

Sunday, August 26th, 2007

Skin testing for penicillin allergy is indicated in patients with a possible or definite past history consistent with immediate hypersensitivity to penicillin and in whom penicillin therapy is indicated and effective alternative antibiotic therapy is not available. Penicillin sensitization occurs by the haptenation mechanism and may involve a number of structural components (or “determinants”) of […]

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